The rat model of Qi deficiency and blood stasis in ischemia stroke was made by using middling aging rats,hunger,tiredness,high fat diets and the occlusion of left common carotid.The general signs,regional cerebral blood flow(rCBF),edema and hemorheology were observed.The contents of thrombox and A 2(TXA 2) and prostalycline(PGI 2) in plasma were detected.The results showed that partial paralysis was found,hemorheologic properties and rCBF markedely lowered ( P <0.01),TXA 2 content in plasma and regional cerebral water content remarkably increased( P <0.01),PGI 2 content in plasma significantly decreased ( P <0.01).