单用口服中药治疗成人病毒性心肌炎随机对照试验的Meta分析
Randomized Controlled Trials of Oral Chinese Herbal Medicine Used Alone in Treatment of Adult Viral Myocarditis: A Meta-analysis
  
DOI:
中文关键词:  口服中药  成人病毒性心肌炎  随机对照试验  Meta分析
英文关键词:Oral Chinese herbal medicine  Adult viral myocarditis  Randomized controlled trial  Meta-analysis
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作者单位
谢冰昕,李树斌,李 勤,张 博,李 乔,李影华 中国中医科学院广安门医院南区北京 102600 
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中文摘要:
      目的 对单用口服中药治疗成人病毒性心肌炎的疗效进行评价。方法 在中国期刊全文数据库(CNKI)、中文科技期刊数据库(VIP)和万方数据库中检索2000年1月至2016年4月发表的单用口服中药治疗成人病毒性心肌炎的随机对照试验文献,对文献进行二次筛选并进行Jadad评分,采用RevMan 5.2软件进行Meta分析。结果 口服中药治疗在改善成人病毒性心肌炎临床症状方面具有明显疗效(OR值为3.32,OR值的95% CI为2.42~4.57, P<0.000 01,I2=0%);在治疗心电图(或动态心电图)异常方面较单独西医常规疗法无明显优势(OR值为1.94,OR值的95% CI为0.98~3.85,P=0.06, I2=71%)。结论 单用口服中药治疗成人病毒性心肌炎可能具有一定的疗效。
英文摘要:
      Objective To investigate the clinical effect of oral Chinese herbal medicine used alone in the treatment of adult viral myocarditis (AVMC). Methods CNKI, VIP, and Wanfang Data were searched for randomized controlled trials of oral Chinese herbal medicine used alone in the treatment of AVMC published from January 2000 to April 2016. The articles were screened twice and the Jadad score was determined. RevMan 5.2 was used for the meta-analysis. Results Oral Chinese herbal medicine had a significant effect in improving the clinical symptoms of AVMC (OR=3.32, 95% CI 2.42-4.57, P<0.000 01, I2=0%). It did not have significant advantages over conventional Western medicine therapy in improving abnormal electrocardiographic findings (or dynamic electrocardiographic findings) (OR=1.94, 95% CI 0.98-3.85, P=0.06, I2=71%). Conclusion Oral Chinese herbal medicine used alone may have a certain effect in the treatment of AVMC.
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