Abstract:Objective To investigate the clinical effect of Qiangli Zhiyun Decoction in the treatment of patients with posterior circulation ischemic vertigo with upper hyperactivity of liver Yang and interior retention of phlegm dampness, as well as its effect on cerebral hemodynamic parameters. Methods A total of 80 patients with posterior circulation ischemic vertigo with upper hyperactivity of liver Yang and interior retention of phlegm dampness were divided into control group and treatment group using a random number table, with 40 patients in each group. The patients in the control group were given conventional medication, and those in the treatment group were given Qiangli Zhiyun Decoction; the course of treatment was 14 days for both groups. Traditional Chinese medicine (TCM) symptom score and vertebrobasilar arterial blood flow were observed before and after treatment; short- and long-term clinical outcomes were observed after 14 days of treatment and at 3 months after treatment; adverse reactions were evaluated in both groups. Results After treatment, compared with the control group, the treatment group had significantly greater reductions in the total score and the scores of TCM symptoms such as dizziness, headache, head heavy as if swathed, dysphoria and irritability, and insomnia and dreaminess (P<0.05), as well as significantly greater increases in mean blood flow velocity of the left vertebral artery, the right vertebral artery, and the basilar artery and significantly greater reductions in pulsatility index of these arteries (P<0.05). The treatment group had significantly better short- and long-term clinical outcomes than the control group (P<0.05). There was no significant difference in the overall incidence rate of adverse reactions (mild bilirubin abnormality, gastrointestinal reactions, and palpitation) between the two groups (P>0.05). Conclusion Qiangli Zhiyun Decoction has a good clinical effect in the treatment of posterior circulation ischemic vertigo with upper hyperactivity of liver Yang and interior retention of phlegm dampness.