Abstract:Objective To investigate the clinical effect of Yiqi Tongluo Jiedu Decoction combined with chemotherapy in the treatment of advanced colorectal cancer. Methods A total of 124 patients with metastatic colorectal cancer were randomly divided into observation group and control group, with 62 patients in each group. The patients in the observation group were given Yiqi Tongluo Jiedu Decoction combined with chemotherapy, and those in the control group were given chemotherapy alone. Results Compared with the control group, the observation group had a significantly better outcome of solid tumor (P<0.05) and significantly lower grades of bone marrow suppression and nausea/vomiting (P<0.05). Conclusion Yiqi Tongluo Jiedu Decoction can improve the outcome of advanced colorectal cancer and reduce bone marrow suppression and nausea/vomiting caused by chemotherapy.