基于板蓝根中(R,S)-告伊春含量研究板蓝根加工方法
A Study on the Processing Method for Radix Isatidis Based on the Content of (R,S)-goitrin
  
DOI:
中文关键词:  板蓝根  产地加工  晒干  烘干  (R,S)-告伊春  软化切制
英文关键词:Radix Isatidis  Processing in the producing area  Sun-drying  Oven-drying  (R,S)-goitrin  Softening and cutting technique
基金项目:国家中药标准化项目(ZYBZH-C-AH-02)
作者单位
王 林,金传山,张 伟,郑晓倩,朱月健 1.安徽中医药大学药学院安徽 合肥 2300122.中药复方安徽省重点实验室安徽 合肥 2300123.中药饮片制造新技术安徽省重点实验室安徽 合肥 2300124.安徽普仁中药饮片有限公司安徽 亳州 236800 
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中文摘要:
      目的 研究不同干燥方法及软化切制方法对板蓝根中(R,S)-告伊春含量的影响,从而建立提升黑龙江产板蓝根质量的加工方法。方法 采用高效液相色谱法对板蓝根中(R,S)-告伊春含量进行测定,比较晒干与烘干板蓝根药材的(R,S)-告伊春含量差异,比较不同投料形式板蓝根颗粒和饮片中(R,S)-告伊春含量差异。结果 60 ℃烘干后的板蓝根药材中(R,S)-告伊春含量高于晒干的板蓝根药材,且能明显缩短板蓝根药材的产地干燥时间;经软化切制的板蓝根饮片中(R,S)-告伊春含量明显高于板蓝根粗颗粒。结论 在板蓝根产地加工过程中,可用烘干法代替晒干法;以板蓝根药材作为中成药投料,建议采用软化切制后的板蓝根饮片。
英文摘要:
      Objective To investigate the influence of different drying methods and softening-cutting methods on the content of (R,S)-goitrin in Radix Isatidis, and to establish a processing method to improve the quality of Radix Isatidis produced in Heilongjiang, China. Methods High-performance liquid chromatography was used to measure the content of (R,S)-goitrin in Radix Isatidis. The content of (R,S)-goitrin was compared between sun-dried and oven-dried Radix Isatidis, as well as between Radix Isatidis granules and decoction pieces with different feeding methods. Results Radix Isatidis dried at a temperature of 60 ℃ had a higher content of (R,S)-goitrin than Radix Isatidis dried in the sun, with a significantly shorter drying time of Radix Isatidis in the producing area. Radix Isatidis decoction pieces after softening and cutting had a higher content of (R,S)-goitrin than Radix Isatidis crude granules. Conclusion The sun-drying method can be replaced by the oven-drying method in the processing of Radix Isatidis in the producing area. If Radix Isatidis is used as the raw material for Chinese patent medicine, it is recommended to use the decoction pieces of Radix Isatidis after softening and cutting.
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