刺血拔罐联合蛇伤冲剂治疗蝮蛇咬伤临床观察
Clinical Effect of Pricking-Cupping Therapy Combined with Sheshang Granule in Treatment of Agkistrodon halys Bite
  
DOI:
中文关键词:  刺血拔罐  毒蛇咬伤  蛇伤冲剂  超敏C反应蛋白  白细胞介素-6
英文关键词:Pricking-cupping therapy  Venomous snake bite  Sheshang Granule  High-sensitivity C-reactive protein  Interleukin-6
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作者单位
李忠志,徐桂琴,袁以洋,韩宁林 安徽中医药大学第一附属医院安徽 合肥 230031 
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中文摘要:
      目的 观察刺血拔罐联合蛇伤冲剂治疗蛇咬伤患者的临床疗效。方法 采用随机数字表法将60例蛇咬伤患者分为对照组和观察组各30例,对照组给予西医基础治疗,观察组在对照组基础上加用刺血拔罐和内服蛇伤冲剂,评估患肢肿胀、疼痛消失时间并检测治疗前后血清超敏C反应蛋白(high-sensitive C-reactive protein,hs-CRP)、白细胞介素-6(interleukin-6,IL-6)水平。结果 观察组患者治疗后肿胀、疼痛症状的改善程度优于对照组(P<0.05);与治疗前比较,两组治疗后hs-CRP、IL-6均显著降低(P<0.05)。两组治疗后hs-CRP降低值比较,差异无统计学意义(P>0.05),观察组IL-6降低值显著大于对照组(P<0.05)。结论 刺血拔罐联合蛇伤冲剂内服可以改善蛇咬伤后肿胀、疼痛的症状,降低血清hs-CRP、IL-6水平。
英文摘要:
      Objective To investigate the clinical effect of pricking-cupping therapy combined with Sheshang Granule in the treatment of Agkistrodon halys bite. Methods A total of 60 patients with Agkistrodon halys bite were divided into observation group and control group using a random number table, with 30 patients in each group. The patients in the control group were given basic Western medicine treatment, and those in the observation group were given pricking-cupping therapy combined with oral Sheshang Granule in addition to the treatment in the control group. The patients were evaluated in terms of swelling of the affected limb, time to pain relief, and serum levels of high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) before and after treatment. Results Compared with the control group, the observation group had significantly greater improvements in the symptoms of swelling and pain (P<0.05), and both groups had significant reductions in hs-CRP and IL-6 after treatment (P<0.05). There was no significant difference in the reduction in hs-CRP after treatment between the two groups (P>0.05), and the observation group had a significantly greater reduction in IL-6 than the control group (P<0.05). Conclusion Pricking-cupping therapy combined with Sheshang Granule can improve the symptoms of swelling and pain after snake bite and reduce the serum levels of hs-CRP and IL-6.
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