Abstract:Objective To investigate the clinical effect of prescribed external wash for eczema in the treatment of infantile eczema with damp- heat accumulation in the skin. Methods A total of 70 children with eczema who met the inclusion criteria were randomly divided into treatment group and control group, with 35 children in each group (3 children in the control group and 2 in the treatment group were lost to follow- up). The children in the treatment group were given the prescribed external wash for eczema, and those in the control group were given calamine lotion; the course of treatment was 2 weeks for both groups. Skin lesion area, Eczema Area and Severity Index (EASI), score of damp- heat accumulation in the skin, and severity of pruritus were evaluated before and after treatment. Results There were significant differences in EASI and score of damp- heat accumulation in the skin between the two groups after treatment (P<0.05), while there was no significant difference in the severity of pruritus between the two groups (P>0.05). Compared with the control group, the treatment group had significantly greater reductions in skin lesion area and score of damp- heat accumulation in the skin after treatment (P<0.05). Conclusion In children with eczema, prescribed external wash for eczema can effectively reduce skin lesion area due to eczema and improve traditional Chinese medicine syndrome and the severity of pruritus.