经伤椎置单向椎弓根螺钉结合十七味大活血胶囊治疗无神经损伤胸腰椎压缩性骨折疗效观察
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Clinical Effect of Oneway Pedicle Screw Placement via the Injured Vertebrae Combined with Shiqiwei Dahuoxue Capsule in Treatment of Thoracolumbar Vertebral Compression Fracture without Nerve Injury
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    目的 观察伤椎置入单向椎弓根螺钉结合十七味大活血胶囊口服在无神经损伤胸腰椎压缩性骨折治疗中的效果。方法 将67例无神经损伤胸腰椎骨折患者,根据患者最终选取的治疗方案分为对照组(n=45)和观察组(n=22)。对照组给予跨伤椎固定的基础上再经伤椎置入单向椎弓根螺钉固定,观察组在对照组的基础上使用自制十七味大活血胶囊口服。分别观察两组治疗前、治疗后1周、治疗后3个月椎前缘高度、椎中缘高度和后凸角度,视觉模拟量表(visual analogue scale,VAS)评分,日本骨科协会(Japanese Orthopaedic Association,JOA)评分。结果 与治疗前比较,两组治疗后1周、3个月椎前缘高度、椎中缘高度均明显增加(P<0.05),后凸角度均明显减小(P<0.05);观察组治疗后3个月椎前缘、椎中缘高度均明显高于对照组(P<0.05)。与治疗前比较,两组治疗后VAS评分在治疗后1周、3个月均明显减少(P<0.05),JOA评分均明显增加(P<0.05)。观察组治疗后VAS评分在治疗后1周、3个月均显著低于对照组(P<0.05),JOA评分明显高于对照组(P<0.05)。结论 经伤椎置入单向椎弓根螺钉结合十七味大活血胶囊口服更利于伤椎前中柱交界处的复位,临床疗效更好。

    Abstract:

    Objective To investigate the clinical effect of oneway pedicle screw placement via the injured vertebrae combined with Shiqiwei Dahuoxue Capsule in the treatment of thoracolumbar vertebral compression fracture without nerve injury.Methods A total of 67 patients with thoracolumbar vertebral compression fracture without nerve injury were enrolled, and according to the treatment regimen they selected, they were divided into control group with 45 patients and observation group with 22 patients. The patients in the control group were given fixation across the injured vertebrae combined with oneway pedicle screw placement via the injured vertebrae, and those in the observation group were given selfmade Shiqiwei Dahuoxue Capsule in addition to the treatment in the control group.Anterior height, midline height, and kyphosis of the injured vertebrae, Visual Analogue Scale (VAS) score, and Japanese Orthopaedic Association (JOA) score were observed before treatment and at 1 week and 3 months after treatment.Results At 1 week and 3 months after treatment, both groups had significant increases in anterior height and midline height of the injured vertebrae (P<0.05) and a significant reduction in kyphosis of the injured vertebrae (P<0.05); at 3 months after treatment, the observation group had significantly higher anterior height and midline height of the injured vertebrae than the control group (P<0.05). At 1 week and 3 months after treatment, both groups had a significant reduction in VAS score (P<0.05) and a significant increase in JOA score (P<0.05), and the observation group had a significantly lower VAS score and a significantly higher JOA score compared with the control group (both P<0.05).Conclusion Oneway pedicle screw placement via the injured vertebrae combined with Shiqiwei Dahuoxue Capsule helps with the reduction at the junction of the anterior and central column of the injured vertebrae and thus has a good clinical effect.

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金孝艺,樊新甫,杨利跃,刘素明,蒋 伟,程 辉,赵 祥,杨 名,吴德林.经伤椎置单向椎弓根螺钉结合十七味大活血胶囊治疗无神经损伤胸腰椎压缩性骨折疗效观察[J].安徽中医药大学学报,2018,37(4):40-44

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  • 在线发布日期: 2018-08-09