Abstract:Objective To investigate the clinical effect of oneway pedicle screw placement via the injured vertebrae combined with Shiqiwei Dahuoxue Capsule in the treatment of thoracolumbar vertebral compression fracture without nerve injury.Methods A total of 67 patients with thoracolumbar vertebral compression fracture without nerve injury were enrolled, and according to the treatment regimen they selected, they were divided into control group with 45 patients and observation group with 22 patients. The patients in the control group were given fixation across the injured vertebrae combined with oneway pedicle screw placement via the injured vertebrae, and those in the observation group were given selfmade Shiqiwei Dahuoxue Capsule in addition to the treatment in the control group.Anterior height, midline height, and kyphosis of the injured vertebrae, Visual Analogue Scale (VAS) score, and Japanese Orthopaedic Association (JOA) score were observed before treatment and at 1 week and 3 months after treatment.Results At 1 week and 3 months after treatment, both groups had significant increases in anterior height and midline height of the injured vertebrae (P<0.05) and a significant reduction in kyphosis of the injured vertebrae (P<0.05); at 3 months after treatment, the observation group had significantly higher anterior height and midline height of the injured vertebrae than the control group (P<0.05). At 1 week and 3 months after treatment, both groups had a significant reduction in VAS score (P<0.05) and a significant increase in JOA score (P<0.05), and the observation group had a significantly lower VAS score and a significantly higher JOA score compared with the control group (both P<0.05).Conclusion Oneway pedicle screw placement via the injured vertebrae combined with Shiqiwei Dahuoxue Capsule helps with the reduction at the junction of the anterior and central column of the injured vertebrae and thus has a good clinical effect.