Abstract:Objective To investigate the clinical effect of Jiawei Lizhong Decoction combined with indirect moxibustion in the treatment of atrophic antral gastritis with deficient cold of spleen and stomach. Methods A total of 60 patients with chronic atrophic antral gastritis with deficient cold of spleen and stomach were divided into control group and observation group using a random number table, with 30 patients in each group. The patients in the control group were given oral Weifuchun Tablet, and those in the observation group were given Jiawei Lizhong Decoction combined with indirect moxibustion. The course of treatment was 12 weeks for both groups. ELISA was used to measure the serum levels of pepsinogen Ⅰ (PGⅠ), pepsinogen Ⅱ (PGⅡ), and gastrin-17, and PGⅠ/PGⅡ ratio was calculated. Results The observation group had significantly better clinical outcomes than the control group (P<0.05). At the end of the 12-week treatment, both groups had significant increases in PGⅠ, PGⅠ/PGⅡ ratio, and gastrin-17 and a significant reduction in PGⅡ (P<0.05), and compared with the control group, the observation group had significantly higher PGⅠ level, PGⅠ/PGⅡ ratio, and gastrin-17 level and a significantly lower PGⅡ level (P<0.05). Conclusion Jiawei Lizhong Decoction combined with indirect moxibustion has a good clinical effect in the treatment of chronic atrophic antral gastritis with deficient cold of spleen and stomach.