理中汤加味联合隔物灸治疗脾胃虚寒型萎缩性胃窦炎疗效观察
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Clinical Effect of Jiawei Lizhong Decoction Combined with Indirect Moxibustionin Treatment of Atrophic Antral Gastritis with Deficient Cold of Spleen and Stomach
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    摘要:

    目的 观察理中汤加味联合隔物灸治疗脾胃虚寒型慢性萎缩性胃窦炎的临床疗效。方法 共纳入60例脾胃虚寒型慢性萎缩性胃窦炎患者,采用随机数字法将其分为对照组和观察组,每组30例,对照组采用胃复春片口服,观察组采用理中汤加味联合隔物灸治疗,疗程均为12周,采用酶联免疫吸附法检测血清胃蛋白酶原(pepsinogen,PG)Ⅰ、PGⅡ和促胃液素-17水平及PGⅠ/PGⅡ比值。结果 观察组临床疗效明显优于对照组(P<0.05)。两组治疗第12周末与治疗前比较,PGⅠ水平升高,PGⅡ水平降低,PGⅠ/PGⅡ比值增高,促胃液素-17水平升高,差异均有统计学意义(P<0.05)。治疗第12周末,观察组较对照组PGⅠ水平升高,PGⅡ水平降低,PGⅠ/PGⅡ比值升高,促胃液素-17水平升高,差异均有统计学意义(P<0.05)。结论 理中汤加味联合隔物灸治疗脾胃虚寒型慢性萎缩性胃窦炎有较好的临床疗效。

    Abstract:

    Objective To investigate the clinical effect of Jiawei Lizhong Decoction combined with indirect moxibustion in the treatment of atrophic antral gastritis with deficient cold of spleen and stomach. Methods A total of 60 patients with chronic atrophic antral gastritis with deficient cold of spleen and stomach were divided into control group and observation group using a random number table, with 30 patients in each group. The patients in the control group were given oral Weifuchun Tablet, and those in the observation group were given Jiawei Lizhong Decoction combined with indirect moxibustion. The course of treatment was 12 weeks for both groups. ELISA was used to measure the serum levels of pepsinogen Ⅰ (PGⅠ), pepsinogen Ⅱ (PGⅡ), and gastrin-17, and PGⅠ/PGⅡ ratio was calculated. Results The observation group had significantly better clinical outcomes than the control group (P<0.05). At the end of the 12-week treatment, both groups had significant increases in PGⅠ, PGⅠ/PGⅡ ratio, and gastrin-17 and a significant reduction in PGⅡ (P<0.05), and compared with the control group, the observation group had significantly higher PGⅠ level, PGⅠ/PGⅡ ratio, and gastrin-17 level and a significantly lower PGⅡ level (P<0.05). Conclusion Jiawei Lizhong Decoction combined with indirect moxibustion has a good clinical effect in the treatment of chronic atrophic antral gastritis with deficient cold of spleen and stomach.

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孙 建.理中汤加味联合隔物灸治疗脾胃虚寒型萎缩性胃窦炎疗效观察[J].安徽中医药大学学报,2018,37(3):45-48

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  • 在线发布日期: 2018-06-08