Abstract:Objective To investigate the clinical effect of Lai's Tongyuan acupoint thread- embedding therapy in the treatment of chloasma. Methods A total of 60 female patients with chloasma were randomly divided into treatment group and control group using a random number table, with 30 patients in each group. The patients in the treatment group were given Lai's Tongyuan acupoint thread- embedding therapy, and those in the control group were given oral vitamin C and vitamin E, as well as external application of hydroquinone cream. The course of treatment was 6 months for both groups. The scores of the area of skin lesion caused by chloasma and color were observed before and after treatment to observe clinical outcome. Results Both groups had significant reductions in the scores of the area of skin lesion caused by chloasma and color and total score after treatment (P<0.05). The treatment group had significantly greater reductions in the score of the area of skin lesion caused by chloasma and total score than the control group after treatment (P<0.05). There was a significant difference in the distribution of clinical outcomes between the two groups (P<0.05). Conclusion Lai's Tongyuan acupoint thread- embedding therapy has a marked clinical effect in the treatment of chloasma.