基于R软件单组率Meta分析研究9种中医体质的人群分布
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安徽中医药大学校级探索性科研项目(2021zxts11)


Study on Population Distribution of Nine Traditional Chinese Medicine Constitutions Based on Single Group Rate Meta Analysis of R Software
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    目的 对中国人群中医体质类型分布情况进行系统评价,为9种中医体质类型全国常模的建立提供循证医学证据。方法 在中国知网、万方数据知识服务平台、维普网、PubMed数据库、Cochrane数据库中检索9种中医体质类型流行病学调查的文献,采用R软件单组率Meta分析对9种中医体质类型的构成比进行合并,根据构成比的潜在影响因素的Meta回归分析结果进行亚组分析。结果 共纳入19篇文献,总样本量为175 331。Meta分析结果显示,平和质、气虚质、阳虚质、阴虚质、痰湿质、湿热质、血瘀质、气郁质、特禀质的构成比分别为0.29(95% CI:0.23~0.36)、0.15(95% CI:0.13~0.18)、0.15(95% CI:0.13~0.18)、0.07(95% CI:0.05~0.10)、0.09(95% CI:0.07~0.12)、0.08(95% CI:0.06~0.10)、0.04(95% CI:0.03~0.05)、0.06(95% CI:0.05~0.08)、0.03(95% CI:0.02~0.04),“男女性别比”是阴虚质构成比的影响因素,“是否兼夹”是阴虚质、痰湿质、湿热质、血瘀质构成比的影响因素,“地区”是平和质、血瘀质、气郁质、特禀质构成比的影响因素。结论 中国人群平和质比例不足1/3,气虚质、阳虚质是最常见的偏颇体质,地域是人群体质的主要影响因素,中医体质类型调查报告有待规范。

    Abstract:

    Objective to systematically evaluate the distribution of traditional Chinese medicine (TCM) constitution types in Chinese population, and to provide evidence-based medicine for the establishment of national norm of nine TCM constitution types. Methods We searched CNKI, Wanfang Data knowledge service platform, Chongqing VIP, PubMed database and Cochrane database for the literature of epidemiological investigation of nine TCM constitution types. We pooled the constituent ratios of nine TCM constitution types by using single group rate meta analysis in R software, and conducted subgroup analysis according to the results of meta regression analysis of potential influencing factors of constituent ratio. Results A total of 19 articles with a total sample size of 175 331 cases were included. The results of meta-analysis showed that the constituent ratios of balanced constitution, Qi deficiency constitution, Yang deficiency constitution, Yin deficiency constitution, phlegm dampness constitution, damp heat constitution, blood stasis constitution, Qi stagnation constitution and special inherited constitution were 0.29(95% CI:0.23~0.36),0.15(95% CI:0.13~0.18),0.15(95% CI:0.13~0.18),0.07(95% CI:0.05~0.10),0.09(95% CI:0.07~0.12),0.08(95% CI:0.06~0.10),0.04(95% CI:0.03~0.05), 0.06(95% CI:0.05~0.08),0.03(95% CI:0.02~0.04), respectively. "male to female ratio" was the influencing factor of the constituent ratio of Yin deficiency constitution, "whether mixed" was the influencing factor of the constituent ratio of Yin deficiency constitution, phlegm dampness constitution, damp heat constitution and blood stasis constitution, "region" was the influencing factor of the constituent ratio of balanced constitution, blood stasis constitution, Qi stagnation constitution and special inherited constitution. Constitution The proportion of Chinese people with balanced constitution is less than 1/3. Qi deficiency constitution and Yang deficiency constitution are the most common imbalanced constitution. Region is the main influencing factor of peoples constitution. The investigation report of TCM constitution types still needs to be standardized.

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姚实林.基于R软件单组率Meta分析研究9种中医体质的人群分布[J].安徽中医药大学学报,2021,40(4):99-104

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  • 在线发布日期: 2021-08-14