目的 观察消瘤通腑散膏摩防治化学治疗后消化道反应的疗效。方法 将60例化学治疗患者随机分为治疗组和对照组各30例，治疗组在化学治疗期间使用消瘤通腑散膏摩联合常规西医对症处理，对照组仅予常规西医对症处理，比较两组患者化学治疗后恶心、呕吐及便秘的情况。结果 治疗组在延迟性呕吐观察期总有效率高于对照组（P＜0.05），且可以降低恶心、呕吐发生的程度（P＜0.05），但在急性呕吐观察期优势不明显（P＞0.05）。治疗组防治化学治疗后便秘的有效率高于对照组，差异有统计学意义（P＜0.05）。结论 消瘤通腑散膏摩可以有效改善化学治疗后的延迟性呕吐及便秘症状，提高患者的生活质量。
Objective To investigate the clinical effect of ointment rubbing with Xiaoliu Tongfu Powder in the prevention and treatment of gastrointestinal reactions after chemotherapy. Methods A total of 60 patients receiving chemotherapy were randomly divided into treatment group and control group, with 30 patients in each group. The patients in the treatment group were given ointment rubbing with Xiaoliu Tongfu Powder combined with conventional Western medicine symptomatic treatment during chemotherapy, and those in the control group were given conventional Western medicine symptomatic treatment alone. The two groups were compared in terms of nausea, vomiting, and constipation after chemotherapy. Results Compared with the control group, the treatment group had a significantly higher overall response rate of delayed vomiting during observation (P<0.05) and a significant reduction in the degree of nausea and vomiting (P<0.05), but with no marked advantage during the observation period of acute vomiting (P>0.05). Compared with the control group, the treatment group had a significantly higher response rate for the prevention and treatment of constipation after chemotherapy (P<0.05). Conclusion Ointment rubbing with Xiaoliu Tongfu Powder can effectively improve the symptoms of delayed vomiting and constipation after chemotherapy and thus improve patients' quality of life.
朱治法,苏 丽,夏 霖,张 梅.消瘤通腑散膏摩防治化学治疗后消化道反应临床观察[J].安徽中医药大学学报,2021,40(2):27-31复制