Objective To investigate the clinical effect of elongated needle acupuncture at the governor vessel in the treatment of post-stoke myodystonia. Methods A total of 60 patients with post-stroke myodystonia were randomly divided into observation group and control group, with 30 patients in each group. The patients in the observation group were given elongated needle acupuncture at the governor vessel, and those in the control group were given conventional acupuncture. Both groups were treated for two courses, with 21 days in total. Modified Ashworth Scale (MAS) and clinic spasticity index (CSI) were used to evaluate muscle tension; Fugl-Meyer motor assessment (FMA) and modified Barthel index (MBI) were used to evaluate activity of daily living. MAS grade was determined for each patient to evaluate clinical outcome. Results The observation group had a significantly better clinical outcome than the control group (P<0.05). After treatment, both groups had significant reductions in MAS and CSI scores (P<0.05) and significant increases in FMA and MBI scores (P<0.05), and compared with the control group, the treatment group had a significantly greater reduction in MAS score (P<0.05) and significantly greater increases in FMA and MBI (P<0.05).Conclusion Elongated needle acupuncture at the governor vessel can improve limb spasm and quality of life in patients with post-stoke myodystonia.