Abstract:Objective To investigate the loss of Radix Paeoniae Alba decoction pieces with different thicknesses and the transfer rate and extract yield of its standard decoction, and to evaluate the influence of decoction piece thickness on the quality of Radix Paeoniae Alba. Methods Radix Paeoniae Alba decoction pieces with different thicknesses were prepared, and chip rate, blanking rate, and warping rate were calculated. The standard decoction of Radix Paeoniae Alba decoction pieces with different thicknesses was prepared to measure extract yield, and high-performance liquid chromatography was used to measure the main components in Radix Paeoniae Alba decoction pieces and decoction and calculate transfer rate. Results The chip rate, blanking rate, and warping rate decreased with the increase in thickness, and the extract yield of the standard decoction of Radix Paeoniae Alba decoction pieces was inversely proportional to the transfer rate of each component and the thickness of Radix Paeoniae Alba decoction pieces. Conclusion Based on this study and the actual situation of industrial production, the thickness of Bozhou Radix Paeoniae Alba decoction pieces is recommended to be about 2 mm.