复方白芍颗粒质量控制研究
DOI:
作者:
作者单位:

作者简介:

通讯作者:

基金项目:

安徽省科技攻关项目(12010402084);安徽省高校省级自然科学研究项目(KJ2013z181)


A Study of Quality Control of Compound Radix Paeoniae Alba Granule
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
    摘要:

    目的 建立复方白芍颗粒的质量标准。方法 采用薄层色谱法对制剂中的白芍﹑泽泻进行定性鉴别,采用高效液相色谱法测定制剂中芍药苷含量。结果 薄层色谱斑点清晰,且阴性对照无干扰;芍药苷浓度在33.35~333.50 μg/mL范围内与峰面积的线性关系良好,平均回收率为97.39%(RSD=1.35%,n=6)。结论 所建立的方法操作简单,重复性好,可有效控制复方白芍颗粒质量。

    Abstract:

    Objective To establish a quality standard for Compound Radix Paeoniae Alba Granule. Methods The qualitative identification of Radix Paeoniae Alba and Rhizoma Alismatis in Compound Radix Paeoniae Alba Granule was performed by thin-layer chromatography (TLC), and the content of paeoniflorin in Compound Radix Paeoniae Alba Granule was determined by high-performance liquid chromatography. Results The relevant spots of Radix Paeoniae Alba and Rhizoma Alismatis on TLC plates were clear without interference from the negative control. A good linear relationship with peak area was achieved when the concentration of paeoniflorin ranged between 33.35 and 333.5 μg/mL. The average recovery rate was 97.39%, and the relative standard deviation was 1.35% (n=6). Conclusion The established method is simple and repeatable to effectively control the quality of Compound Radix Paeoniae Alba Granule.

    参考文献
    相似文献
    引证文献
引用本文

王 帆,储晓琴,桂双英.复方白芍颗粒质量控制研究[J].安徽中医药大学学报,2015,34(3):81-83

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2015-06-04